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AneurysmDataBank:
an integrated disease model.

A research infrastructure designed to connect clinical, imaging and experimental information—supporting collaboration across physics, biology, pathology and care.

Research infrastructureMulticentre collaborationControlled access
Purpose

Connect the levels
of disease.

Intracranial aneurysms are shaped by interacting biological, mechanical, anatomical and clinical factors.

The AneurysmDataBank provides infrastructure intended to facilitate responsible scientific use of information, promote cross-field interaction and support an integrated view of disease. Its long-term purpose includes disease monitoring, validated information, clinician decision support and services for the scientific community.

From source to insight

A governed path for
multimodal data.

01

Contribute

Approved collaborating centres contribute structured clinical, imaging or experimental information.

02

Harmonise

Information is aligned to common formats and Common Data Elements where applicable.

03

Govern

Data are handled through ethics, access-control and collaboration requirements.

04

Investigate

Researchers explore relationships across scales and develop new clinically relevant questions.

Information architecture

Multiple scales.
One research context.

The resource is described as including structured and imaging information spanning molecular, cellular, organ, patient and population levels. It has been populated through projects including @neurIST, AneuX and the ISGC Intracranial Aneurysm working group.

MolecularMechanisms
CellularBiology
OrganVessels & brain
PatientClinical course
PopulationPatterns
01 / CLINICAL

Presentation and outcomes

Patient condition, aneurysm characteristics, treatments and follow-up outcomes.

02 / IMAGING

Multimedia sources

Imaging information associated with controlled multimedia archiving workflows.

03 / EXPERIMENTAL

In vitro and in vivo

Experimental information may be integrated where governance and structure permit.

Collaborate with the ADB.

New centres require formal ethical approval and coordination with the ADB management office.

Contact management